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Students at the MD Anderson School of Health Professions Program in Cytogenetic Technology are required to perform regular service work in cytogenetic technology laboratories as a part of their internship education. This allows students to become competent with cytogenetic technology techniques and prepares them to enter the workforce with the necessary entry-level competencies to function in any routine cytogenetic technology laboratory.
All laboratory service work performed by students will be monitored by the assigned preceptor in each laboratory. Note: If the student must be left alone in any laboratory area for an extended period, please notify the Program Director to ensure proper supervision of the student.
Clinical cytogenetics is the specialty that studies cell division and the structure of chromosomes as applied to the diagnosis and monitoring of acquired and inherited abnormalities. The most widely recognized use of cytogenetics is the study of inherited disorders through prenatal diagnosis by amniocentesis and chorionic villus sampling or postnatal diagnosis by peripheral blood studies. Cytogenetic technology is also used in the study of acquired chromosomal abnormalities present in various forms of cancer.
In recent years the Human Genome Project has greatly affected genetic testing at all levels. The discovery of new genes and the identification of the DNA sequence and location of diagnostically relevant genes have lead to the development of the new field of molecular cytogenetics.
It is now widely accepted that most human disease is caused in part by a genetic defect. Identification of these genetic abnormalities has become an essential part in the medical treatment of patients in many specialty institutions across the country.
The primary responsibility of the clinical cytogenetic technologist is the analysis and karyotyping of human chromosome preparations. The clinical genetics technologist must be able to perform all aspects of the cytogenetic procedure. Our personalized portal helps you refer your patients and communicate with their MD Anderson care team.
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Jump To:. Review in Clinical Cytogenetics. Students do not work with material that is used for patient reporting. The students learn the specialized staining techniques required to differentiate special regions of human chromosomes and to induce specific banding patterns necessary for the identification of genetic changes.
Students are instructed in the methodology required to scan, review, count cells and analyze slides for metaphase spreads. Detailed instructions in imaging of cytogenetic preparations both with conventional photography and darkroom techniques as well as with automated computer imaging systems are included in the curriculum. Students spend a significant portion of the course mastering the pattern recognition necessary for accurate identification of the normal human chromosomes banding pattern utilizing the GTG banding technique.
Students become familiar with common abnormal banding patterns associated with genetic disease. DNA probe methodology is an important part of the curriculum and students become proficient in labeling of DNA with fluorescent dyes and hybridization of DNA to target DNA both on agarose gels and glass microscope slides.
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